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Journal Articles

Spread of radiation application to biological studies

Watanabe, Hiroshi

Baiosaiensu To Indasutori, 61(2), p.53 - 56, 2003/02

no abstracts in English

Journal Articles

A Novel protein that recognizes DNA strand break

Narumi, Issei; Sato, Katsuya; Kikuchi, Masahiro

JAERI-Conf 2002-005, p.158 - 171, 2002/03

${it Deinococcus radiodurans}$ is characterized by its extraordinary resistance to the lethal and mutagenic effects of ionizing and ultraviolet irradiations and many other DNA-damaging agents. By analyzing a DNA repair-deficient mutant strain, we discovered that a novel protein participates in the extreme radiation resistance of ${it D. radiodurans}$. The protein (designated PprA for promoting prominent repair) can recognize DNA strand breaks. Further, PprA would protect irradiation-damaged DNA from exonuclease activity and consequent degradation and thereby ensure DNA repair processes could function. Beside DNA-binding ability, PprA can promote the activities of DNA ligase and RecA, suggesting that PprA functions as a DNA repair-promoting protein to potentiate the effectiveness of DNA repair. These properties enable PprA to use the widespread application ${it in vivo}$ and ${it in vitro}$.

Oral presentation

Simulation of chromosomal structural change as a radiation target

Ouchi, Noriyuki

no journal, , 

no abstracts in English

Oral presentation

Secondary structural change of histone H2A/H2B induced by DNA damage responses

Izumi, Yudai; Yamamoto, Satoshi*; Fujii, Kentaro; Yokoya, Akinari

no journal, , 

no abstracts in English

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